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ea0090rc2.4 | Rapid Communications 2: Thyroid | ECE2023

Cell free DNA Integrity index to differentiate benign from malignant thyroid nodules

Tarafdar Soham , Dutta Susmita , P. Bhattacharyya Nitai , Mukhopadhyay Pradip , Ghosh Sujoy

Introduction: Cell-free DNA (cfDNA) integrity in plasma has been investigated as a non-invasive marker in cancer. Thyroid cancer the most common endocrine malignancy sometimes presents as indeterminate nodules and difficult to diagnose without histopathology.Aim of the study: The present study aims to test the hypothesis that the presence of longer DNA strands circulating in plasma can be considered a marker for thyroid cancer.Meth...